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Single-dose pentamidine substantially reduces viability of trypanosomes in human East African trypanosomiasis

Examination of viability of trypomastigotes before and after single-dose pentamidine treatment demonstrated that single-dose pentamidine substantially affected motility of trypomastigotes, a proxy of drug efficacy. This suggests that single-dose pentamidine may be of added value to bridge time until...

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Detalles Bibliográficos
Autores principales: van Genderen, Perry J J, Nouwen, Jan L, De Mendonça Melo, Mariana, Rijnders, Bart J A, van Hellemond, Jaap J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8393691/
https://www.ncbi.nlm.nih.gov/pubmed/34008033
http://dx.doi.org/10.1093/jtm/taab080