Cargando…
BRIE2: computational identification of splicing phenotypes from single-cell transcriptomic experiments
RNA splicing is an important driver of heterogeneity in single cells through the expression of alternative transcripts and as a determinant of transcriptional kinetics. However, the intrinsic coverage limitations of scRNA-seq technologies make it challenging to associate specific splicing events to...
Autores principales: | , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8393734/ https://www.ncbi.nlm.nih.gov/pubmed/34452629 http://dx.doi.org/10.1186/s13059-021-02461-5 |