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BRIE2: computational identification of splicing phenotypes from single-cell transcriptomic experiments
RNA splicing is an important driver of heterogeneity in single cells through the expression of alternative transcripts and as a determinant of transcriptional kinetics. However, the intrinsic coverage limitations of scRNA-seq technologies make it challenging to associate specific splicing events to...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8393734/ https://www.ncbi.nlm.nih.gov/pubmed/34452629 http://dx.doi.org/10.1186/s13059-021-02461-5 |