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SLC7A11 regulated by NRF2 modulates esophageal squamous cell carcinoma radiosensitivity by inhibiting ferroptosis

BACKGROUND: Solute carrier family 7 member 11(SLC7A11) is a component of cysteine/glutamate transporter, which plays a key role in tumor growth; however, its underlying effect on radiosensitivity in esophageal squamous cell carcinoma (ESCC) remains unclear. This study aimed to clarify SLC7A11’s expr...

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Detalles Bibliográficos
Autores principales: Feng, Lei, Zhao, Kaikai, Sun, Liangchao, Yin, Xiaoyang, Zhang, Junpeng, Liu, Conghe, Li, Baosheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8393811/
https://www.ncbi.nlm.nih.gov/pubmed/34446045
http://dx.doi.org/10.1186/s12967-021-03042-7