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Role of PLEXIND1/TGFβ Signaling Axis in Pancreatic Ductal Adenocarcinoma Progression Correlates with the Mutational Status of KRAS

SIMPLE SUMMARY: Pancreatic cancer is among the most lethal cancers. The expression of PLEXIND1, a receptor, is upregulated in many cancers (including pancreatic cancer). Traditionally, PLEXIND1 is known to be involved in neuron development and mediate semaphorin signaling. However, its role and sign...

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Detalles Bibliográficos
Autores principales: Vivekanandhan, Sneha, Madamsetty, Vijay S., Angom, Ramcharan Singh, Dutta, Shamit Kumar, Wang, Enfeng, Caulfield, Thomas, Pletnev, Alexandre A., Upstill-Goddard, Rosanna, Asmann, Yan W., Chang, David, Spaller, Mark R., Mukhopadhyay, Debabrata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8393884/
https://www.ncbi.nlm.nih.gov/pubmed/34439202
http://dx.doi.org/10.3390/cancers13164048