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Harnessing the Nucleolar DNA Damage Response in Cancer Therapy

The nucleoli are subdomains of the nucleus that form around actively transcribed ribosomal RNA (rRNA) genes. They serve as the site of rRNA synthesis and processing, and ribosome assembly. There are 400–600 copies of rRNA genes (rDNA) in human cells and their highly repetitive and transcribed nature...

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Detalles Bibliográficos
Autores principales: Xuan, Jiachen, Gitareja, Kezia, Brajanovski, Natalie, Sanij, Elaine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8393943/
https://www.ncbi.nlm.nih.gov/pubmed/34440328
http://dx.doi.org/10.3390/genes12081156