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A Novel Bispecific Antibody Targeting CD3 and Lewis Y with Potent Therapeutic Efficacy against Gastric Cancer

Lewis Y antigen, a glycan highly expressed on most epithelial cancers, was targeted for cancer treatment but lacked satisfactory results in some intractable and refractory cancers. Thus, it is highly desirable to develop an effective therapy against these cancers, hopefully based on this target. In...

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Detalles Bibliográficos
Autores principales: Chen, Jie, Pan, Zhidi, Han, Lei, Zhou, Yuexian, Zong, Huifang, Wang, Lei, Sun, Rui, Jiang, Hua, Xie, Yueqing, Yuan, Yunsheng, Wu, Mingyuan, Bian, Yanling, Zhang, Baohong, Zhu, Jianwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8393954/
https://www.ncbi.nlm.nih.gov/pubmed/34440263
http://dx.doi.org/10.3390/biomedicines9081059