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Implications of a ‘Third Signal’ in NK Cells

Innate and adaptive immune systems are evolutionarily divergent. Primary signaling in T and B cells depends on somatically rearranged clonotypic receptors. In contrast, NK cells use germline-encoded non-clonotypic receptors such as NCRs, NKG2D, and Ly49H. Proliferation and effector functions of T an...

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Detalles Bibliográficos
Autores principales: Khalil, Mohamed, Wang, Dandan, Hashemi, Elaheh, Terhune, Scott S., Malarkannan, Subramaniam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8393955/
https://www.ncbi.nlm.nih.gov/pubmed/34440725
http://dx.doi.org/10.3390/cells10081955