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Expression of HDACs 1, 3 and 8 Is Upregulated in the Presence of Infiltrating Lymphocytes in Uveal Melanoma

SIMPLE SUMMARY: Uveal melanoma (UM) is an ocular malignancy which is derived from melanocytes in the uveal tract. Epigenetic regulators such as Histone Deacetylase (HDACs) inhibitors are being tested as treatment of UM metastases. Expression of different HDACs is variable, and some are increased in...

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Detalles Bibliográficos
Autores principales: Souri, Zahra, Jochemsen, Aart G., Wierenga, Annemijn P. A., Kroes, Wilma G. M., Verdijk, Rob M., van der Velden, Pieter A., Luyten, Gregorius P. M., Jager, Martine J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8393956/
https://www.ncbi.nlm.nih.gov/pubmed/34439300
http://dx.doi.org/10.3390/cancers13164146