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TRPM2 Oxidation Activates Two Distinct Potassium Channels in Melanoma Cells through Intracellular Calcium Increase

Tumor microenvironments are often characterized by an increase in oxidative stress levels. We studied the response to oxidative stimulation in human primary (IGR39) or metastatic (IGR37) cell lines obtained from the same patient, performing patch-clamp recordings, intracellular calcium ([Ca(2+)](i))...

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Detalles Bibliográficos
Autores principales: Ferrera, Loretta, Barbieri, Raffaella, Picco, Cristiana, Zuccolini, Paolo, Remigante, Alessia, Bertelli, Sara, Fumagalli, Maria Rita, Zifarelli, Giovanni, La Porta, Caterina A. M., Gavazzo, Paola, Pusch, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8393965/
https://www.ncbi.nlm.nih.gov/pubmed/34445066
http://dx.doi.org/10.3390/ijms22168359