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Memantine Protects against Paclitaxel-Induced Cognitive Impairment through Modulation of Neurogenesis and Inflammation in Mice

SIMPLE SUMMARY: Chemotherapy-induced cognitive impairment (CICI) is an increasing awareness due to prolonged survival following cancer chemotherapy in cancer patients. Multiple mechanisms have been proposed for CICI induced by various chemotherapeutic agents; however, hippocampal damage and impaired...

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Detalles Bibliográficos
Autores principales: Sung, Pi-Shan, Chen, Pei-Wen, Yen, Chia-Jui, Shen, Meng-Ru, Chen, Chih-Hung, Tsai, Kuen-Jer, Lin, Chou-Ching K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8394018/
https://www.ncbi.nlm.nih.gov/pubmed/34439331
http://dx.doi.org/10.3390/cancers13164177