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Association of TP53 Alteration with Tissue Specificity and Patient Outcome of IDH1-Mutant Glioma
Since the initial discovery of recurrent isocitrate dehydrogenase 1 (IDH1) mutations at Arg132 in glioma, IDH1 hotspot mutations have been identified in cholangiocarcinoma, chondrosarcoma, leukemia, and various other types of cancer of sporadic incidence. Studies in glioma and leukemia have helped p...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8394030/ https://www.ncbi.nlm.nih.gov/pubmed/34440884 http://dx.doi.org/10.3390/cells10082116 |