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Selective Targeting of Class I Histone Deacetylases in a Model of Human Osteosarcoma

SIMPLE SUMMARY: Osteosarcoma is the predominant form of primary bone cancer and outcomes for patients with metastatic disease have not improved for several decades. Recent genomic and pharmacological studies have implicated dysregulated histone deacetylases as druggable targets to treat several type...

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Detalles Bibliográficos
Autores principales: Torres, Haydee M., VanCleave, Ashley M., Vollmer, Mykayla, Callahan, Dakota L., Smithback, Austyn, Conn, Josephine M., Rodezno-Antunes, Tania, Gao, Zili, Cao, Yuxia, Afeworki, Yohannes, Tao, Jianning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8394112/
https://www.ncbi.nlm.nih.gov/pubmed/34439353
http://dx.doi.org/10.3390/cancers13164199