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From Microspikes to Stress Fibers: Actin Remodeling in Breast Acini Drives Myosin II-Mediated Basement Membrane Invasion

The cellular mechanisms of basement membrane (BM) invasion remain poorly understood. We investigated the invasion-promoting mechanisms of actin cytoskeleton reorganization in BM-covered MCF10A breast acini. High-resolution confocal microscopy has characterized actin cell protrusion formation and fun...

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Detalles Bibliográficos
Autores principales: Eschenbruch, Julian, Dreissen, Georg, Springer, Ronald, Konrad, Jens, Merkel, Rudolf, Hoffmann, Bernd, Noetzel, Erik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8394122/
https://www.ncbi.nlm.nih.gov/pubmed/34440749
http://dx.doi.org/10.3390/cells10081979