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Algorithmically Deduced FREM2 Molecular Pathway Is a Potent Grade and Survival Biomarker of Human Gliomas

SIMPLE SUMMARY: Gliomas are the most common malignant brain tumors with high mortality rates. Recently the role of the FREM2 gene has been shown in glioblastoma progression. Here we reconstructed the FREM2 molecular pathway. We assessed the biomarker capacity of FREM2 expression and its pathway as t...

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Detalles Bibliográficos
Autores principales: Zolotovskaia, Marianna, Tkachev, Victor, Sorokin, Maxim, Garazha, Andrew, Kim, Ella, Kantelhardt, Sven Rainer, Bikar, Sven-Ernö, Zottel, Alja, Šamec, Neja, Kuzmin, Denis, Sprang, Bettina, Moisseev, Alexey, Giese, Alf, Efimov, Victor, Jovčevska, Ivana, Buzdin, Anton
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8394245/
https://www.ncbi.nlm.nih.gov/pubmed/34439271
http://dx.doi.org/10.3390/cancers13164117