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Gene Panel Testing for Breast Cancer Reveals Differential Effect of Prior BRCA1/2 Probability

SIMPLE SUMMARY: Previous studies reporting large gene panels in breast cancer have mainly reported on the contribution of additional genes compared to BRCA1/2. We have shown a very large differential additional effect from non-BRCA genes dependent on a priori likelihood of BRCA1 and BRCA2 combined....

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Detalles Bibliográficos
Autores principales: Evans, D. Gareth, van Veen, Elke M., Woodward, Emma R., Harkness, Elaine F., Ellingford, Jamie M., Bowers, Naomi L., Wallace, Andrew J., Howell, Sacha J., Howell, Anthony, Lalloo, Fiona, Newman, William G., Smith, Miriam J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8394249/
https://www.ncbi.nlm.nih.gov/pubmed/34439310
http://dx.doi.org/10.3390/cancers13164154