The Mutational Landscape of Myeloid Leukaemia in Down Syndrome

SIMPLE SUMMARY: Leukaemia occurs when specific mutations promote aberrant transcriptional and proliferation programs, which drive uncontrolled cell division and inhibit the cell’s capacity to differentiate. In this review, we summarize the most frequent genetic lesions found in myeloid leukaemia of...

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Detalles Bibliográficos
Autores principales: de Castro, Carini Picardi Morais, Cadefau, Maria, Cuartero, Sergi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8394284/
https://www.ncbi.nlm.nih.gov/pubmed/34439298
http://dx.doi.org/10.3390/cancers13164144

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8394284/
https://www.ncbi.nlm.nih.gov/pubmed/34439298
http://dx.doi.org/10.3390/cancers13164144

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