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The Mutational Landscape of Myeloid Leukaemia in Down Syndrome
SIMPLE SUMMARY: Leukaemia occurs when specific mutations promote aberrant transcriptional and proliferation programs, which drive uncontrolled cell division and inhibit the cell’s capacity to differentiate. In this review, we summarize the most frequent genetic lesions found in myeloid leukaemia of...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8394284/ https://www.ncbi.nlm.nih.gov/pubmed/34439298 http://dx.doi.org/10.3390/cancers13164144 |