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Zebrafish Patient-Derived Xenografts Identify Chemo-Response in Pancreatic Ductal Adenocarcinoma Patients

SIMPLE SUMMARY: Treating the PDAC (pancreatic ductal adenocarcinoma) zPDXs (zebrafish patient-derived xenografts) with chemotherapy regimens commonly used, we performed a co-clinical trial testing the predictiveness of the model. We found that zPDX may predict patient outcomes, classifying them into...

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Detalles Bibliográficos
Autores principales: Usai, Alice, Di Franco, Gregorio, Piccardi, Margherita, Cateni, Perla, Pollina, Luca Emanuele, Vivaldi, Caterina, Vasile, Enrico, Funel, Niccola, Palmeri, Matteo, Dente, Luciana, Falcone, Alfredo, Giunchi, Dimitri, Massolo, Alessandro, Raffa, Vittoria, Morelli, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8394309/
https://www.ncbi.nlm.nih.gov/pubmed/34439284
http://dx.doi.org/10.3390/cancers13164131