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Citrate-Coated Superparamagnetic Iron Oxide Nanoparticles Enable a Stable Non-Spilling Loading of T Cells and Their Magnetic Accumulation

SIMPLE SUMMARY: In cancer patients, adoptive T cell transfer shall increase the number of circulating cytotoxic T cells to foster anti-tumor immune responses. In solid tumors, however, lack of lymphocyte infiltration into the tumor impairs treatment efficacy due to the immune-suppressive tumor micro...

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Detalles Bibliográficos
Autores principales: Boosz, Philipp, Pfister, Felix, Stein, Rene, Friedrich, Bernhard, Fester, Lars, Band, Julia, Mühlberger, Marina, Schreiber, Eveline, Lyer, Stefan, Dudziak, Diana, Alexiou, Christoph, Janko, Christina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8394404/
https://www.ncbi.nlm.nih.gov/pubmed/34439296
http://dx.doi.org/10.3390/cancers13164143