MiRNA Let-7a and Let-7d Are Induced by Globotriaosylceramide via NF-kB Activation in Fabry Disease

Background: Fabry disease is a hereditary genetic defect resulting in reduced activity of the enzyme α-galactosidase-A and the accumulation of globotriaosylceramide (Gb3) in body fluids and cells. Gb3 accumulation was especially reported for the vascular endothelium in several organs. Methods: Three...

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Detalles Bibliográficos
Autores principales: Maier, Nadine, Gatterer, Constantin, Haider, Patrick, Salzmann, Manuel, Kaun, Christoph, Speidl, Walter S., Sunder-Plassmann, Gere, Podesser, Bruno K., Wojta, Johann, Graf, Senta, Lenz, Max, Hohensinner, Philipp J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8394417/
https://www.ncbi.nlm.nih.gov/pubmed/34440358
http://dx.doi.org/10.3390/genes12081184

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8394417/
https://www.ncbi.nlm.nih.gov/pubmed/34440358
http://dx.doi.org/10.3390/genes12081184

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