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MEM: An Algorithm for the Reliable Detection of Microsatellite Instability (MSI) on a Small NGS Panel in Colorectal Cancer

SIMPLE SUMMARY: Microsatellite instability (MSI) assessment has become a major issue in the management of colorectal cancer, with the recent approval of anti-PD1 immunotherapies in MSI-metastatic colorectal cancer. The reference PCR method (MSI-PCR) can be costly, time and tissue-consuming. However,...

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Detalles Bibliográficos
Autores principales: Herbreteau, Guillaume, Airaud, Fabrice, Pierre-Noël, Elise, Vallée, Audrey, Bézieau, Stéphane, Théoleyre, Sandrine, Blons, Hélène, Garinet, Simon, Denis, Marc Guillaume
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8394433/
https://www.ncbi.nlm.nih.gov/pubmed/34439357
http://dx.doi.org/10.3390/cancers13164203