The Natural Product β-Escin Targets Cancer and Stromal Cells of the Tumor Microenvironment to Inhibit Ovarian Cancer Metastasis

SIMPLE SUMMARY: β-escin, a component of horse chestnut seed extract, was first identified as an inhibitor of ovarian cancer (OvCa) adhesion/invasion in our high-throughput screening program using a three-dimensional organotypic model assembled from primary human cells and extracellular matrix. The g...

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Detalles Bibliográficos
Autores principales: Kenny, Hilary A., Hart, Peter C., Kordylewicz, Kasjusz, Lal, Madhu, Shen, Min, Kara, Betul, Chen, Yen-Ju, Grassl, Niklas, Alharbi, Yousef, Pattnaik, Bikash R., Watters, Karen M., Patankar, Manish S., Ferrer, Marc, Lengyel, Ernst
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8394501/
https://www.ncbi.nlm.nih.gov/pubmed/34439084
http://dx.doi.org/10.3390/cancers13163931

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8394501/
https://www.ncbi.nlm.nih.gov/pubmed/34439084
http://dx.doi.org/10.3390/cancers13163931

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