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Role of NRF2 in Lung Cancer

The gene expression program induced by NRF2 transcription factor plays a critical role in cell defense responses against a broad variety of cellular stresses, most importantly oxidative stress. NRF2 stability is fine-tuned regulated by KEAP1, which drives its degradation in the absence of oxidative...

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Detalles Bibliográficos
Autores principales: Sánchez-Ortega, Miriam, Carrera, Ana Clara, Garrido, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8394503/
https://www.ncbi.nlm.nih.gov/pubmed/34440648
http://dx.doi.org/10.3390/cells10081879