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Role of NRF2 in Lung Cancer
The gene expression program induced by NRF2 transcription factor plays a critical role in cell defense responses against a broad variety of cellular stresses, most importantly oxidative stress. NRF2 stability is fine-tuned regulated by KEAP1, which drives its degradation in the absence of oxidative...
Autores principales: | Sánchez-Ortega, Miriam, Carrera, Ana Clara, Garrido, Antonio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8394503/ https://www.ncbi.nlm.nih.gov/pubmed/34440648 http://dx.doi.org/10.3390/cells10081879 |
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