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AKAP79 Orchestrates a Cyclic AMP Signalosome Adjacent to Orai1 Ca(2+) Channels
To ensure specificity of response, eukaryotic cells often restrict signalling molecules to sub-cellular regions. The Ca(2+) nanodomain is a spatially confined signal that arises near open Ca(2+) channels. Ca(2+) nanodomains near store-operated Orai1 channels stimulate the protein phosphatase calcine...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8394516/ https://www.ncbi.nlm.nih.gov/pubmed/34458850 http://dx.doi.org/10.1093/function/zqab036 |