Cargando…

AKAP79 Orchestrates a Cyclic AMP Signalosome Adjacent to Orai1 Ca(2+) Channels

To ensure specificity of response, eukaryotic cells often restrict signalling molecules to sub-cellular regions. The Ca(2+) nanodomain is a spatially confined signal that arises near open Ca(2+) channels. Ca(2+) nanodomains near store-operated Orai1 channels stimulate the protein phosphatase calcine...

Descripción completa

Detalles Bibliográficos
Autores principales: Kar, Pulak, Barak, Pradeep, Zerio, Anna, Lin, Yu-Ping, Parekh, Amy J, Watts, Val J, Cooper, Dermot M F, Zaccolo, Manuela, Kramer, Holger, Parekh, Anant B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8394516/
https://www.ncbi.nlm.nih.gov/pubmed/34458850
http://dx.doi.org/10.1093/function/zqab036