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Disruption of RING and PHD Domains of TRIM28 Evokes Differentiation in Human iPSCs
TRIM28, a multi-domain protein, is crucial in the development of mouse embryos and the maintenance of embryonic stem cells’ (ESC) self-renewal potential. As the epigenetic factor modulating chromatin structure, TRIM28 regulates the expression of numerous genes and is associated with progression and...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8394524/ https://www.ncbi.nlm.nih.gov/pubmed/34440702 http://dx.doi.org/10.3390/cells10081933 |