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Disruption of RING and PHD Domains of TRIM28 Evokes Differentiation in Human iPSCs

TRIM28, a multi-domain protein, is crucial in the development of mouse embryos and the maintenance of embryonic stem cells’ (ESC) self-renewal potential. As the epigenetic factor modulating chromatin structure, TRIM28 regulates the expression of numerous genes and is associated with progression and...

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Detalles Bibliográficos
Autores principales: Mazurek, Sylwia, Oleksiewicz, Urszula, Czerwińska, Patrycja, Wróblewska, Joanna, Klimczak, Marta, Wiznerowicz, Maciej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8394524/
https://www.ncbi.nlm.nih.gov/pubmed/34440702
http://dx.doi.org/10.3390/cells10081933