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Activation of Nrf2 in Astrocytes Suppressed PD-Like Phenotypes via Antioxidant and Autophagy Pathways in Rat and Drosophila Models

The oxidative-stress-induced impairment of autophagy plays a critical role in the pathogenesis of Parkinson’s disease (PD). In this study, we investigated whether the alteration of Nrf2 in astrocytes protected against 6-OHDA (6-hydroxydopamine)- and rotenone-induced PD-like phenotypes, using 6-OHDA-...

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Detalles Bibliográficos
Autores principales:	Guo, Qing, Wang, Bing, Wang, Xiaobo, Smith, Wanli W., Zhu, Yi, Liu, Zhaohui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8394528/ https://www.ncbi.nlm.nih.gov/pubmed/34440619 http://dx.doi.org/10.3390/cells10081850

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