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Overexpression and Activation of αvβ3 Integrin Differentially Affects TGFβ2 Signaling in Human Trabecular Meshwork Cells

Studies from our laboratory have suggested that activation of αvβ3 integrin-mediated signaling could contribute to the fibrotic-like changes observed in primary open angle glaucoma (POAG) and glucocorticoid-induced glaucoma. To determine how αvβ3 integrin signaling could be involved in this process,...

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Detalles Bibliográficos
Autores principales: Filla, Mark S., Meyer, Kristy K., Faralli, Jennifer A., Peters, Donna M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8394542/
https://www.ncbi.nlm.nih.gov/pubmed/34440692
http://dx.doi.org/10.3390/cells10081923