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Anti-Obesity Drug Orlistat Alleviates Western-Diet-Driven Colitis-Associated Colon Cancer via Inhibition of STAT3 and NF-κB-Mediated Signaling

Many researchers have argued that Western diet (WD)-induced obesity accelerates inflammation and that inflammation is a link between obesity and colorectal cancer (CRC). This study investigated the effect of WDs on the development and progression of colitis-associated colon cancer (CAC) and the effi...

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Detalles Bibliográficos
Autores principales: Jin, Bo-Ram, Kim, Hyo-Jung, Sim, Seo-Ah, Lee, Minho, An, Hyo-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8394553/
https://www.ncbi.nlm.nih.gov/pubmed/34440829
http://dx.doi.org/10.3390/cells10082060