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Protective and Therapeutic Effects of an IL-15:IL-15Rα-Secreting Cell-Based Cancer Vaccine Using a Baculovirus System

SIMPLE SUMMARY: Interleukin (IL) 15 is a proinflammatory cytokine and is well-known as an efficacious cytokine for cancer immunotherapy. Interestingly, the IL-15:IL-15Rα complex, a self-assembling form of IL-15 and its soluble receptor α (IL-15Rα), has shown greater antitumor activity than IL-15 its...

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Detalles Bibliográficos
Autores principales: Do-Thi, Van Anh, Lee, Hayyoung, Jeong, Hye Jin, Lee, Jie-Oh, Kim, Young Sang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8394727/
https://www.ncbi.nlm.nih.gov/pubmed/34439192
http://dx.doi.org/10.3390/cancers13164039