Necrostatin-1 Supplementation to Islet Tissue Culture Enhances the In-Vitro Development and Graft Function of Young Porcine Islets

Pre-weaned porcine islets (PPIs) represent an unlimited source for islet transplantation but are functionally immature. We previously showed that necrostatin-1 (Nec-1) immediately after islet isolation enhanced the in vitro development of PPIs. Here, we examined the impact of Nec-1 on the in vivo fu...

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Detalles Bibliográficos
Autores principales: Lau, Hien, Li, Shiri, Corrales, Nicole, Rodriguez, Samuel, Mohammadi, Mohammadreza, Alexander, Michael, de Vos, Paul, Lakey, Jonathan RT
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8394857/
https://www.ncbi.nlm.nih.gov/pubmed/34445075
http://dx.doi.org/10.3390/ijms22168367

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8394857/
https://www.ncbi.nlm.nih.gov/pubmed/34445075
http://dx.doi.org/10.3390/ijms22168367

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