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Necrostatin-1 Supplementation to Islet Tissue Culture Enhances the In-Vitro Development and Graft Function of Young Porcine Islets
Pre-weaned porcine islets (PPIs) represent an unlimited source for islet transplantation but are functionally immature. We previously showed that necrostatin-1 (Nec-1) immediately after islet isolation enhanced the in vitro development of PPIs. Here, we examined the impact of Nec-1 on the in vivo fu...
Autores principales: | Lau, Hien, Li, Shiri, Corrales, Nicole, Rodriguez, Samuel, Mohammadi, Mohammadreza, Alexander, Michael, de Vos, Paul, Lakey, Jonathan RT |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8394857/ https://www.ncbi.nlm.nih.gov/pubmed/34445075 http://dx.doi.org/10.3390/ijms22168367 |
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