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Epigenetic Alterations Upstream and Downstream of p53 Signaling in Colorectal Carcinoma

SIMPLE SUMMARY: Colorectal cancer (CRC) belongs to the most common cancer types. It is well known that half of all CRC possess missense mutations in the TP53 tumor suppressor gene. However, the entire signaling cascade upstream and downstream of the p53 protein may also contribute to CRC development...

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Detalles Bibliográficos
Autores principales: Tomicic, Maja T., Dawood, Mona, Efferth, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8394868/
https://www.ncbi.nlm.nih.gov/pubmed/34439227
http://dx.doi.org/10.3390/cancers13164072