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Epigenetic Alterations Upstream and Downstream of p53 Signaling in Colorectal Carcinoma
SIMPLE SUMMARY: Colorectal cancer (CRC) belongs to the most common cancer types. It is well known that half of all CRC possess missense mutations in the TP53 tumor suppressor gene. However, the entire signaling cascade upstream and downstream of the p53 protein may also contribute to CRC development...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8394868/ https://www.ncbi.nlm.nih.gov/pubmed/34439227 http://dx.doi.org/10.3390/cancers13164072 |