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Characterization of Permeability Barrier Dysfunction in a Murine Model of Cutaneous Field Cancerization Following Chronic UV-B Irradiation: Implications for the Pathogenesis of Skin Cancer

SIMPLE SUMMARY: In the present work, we developed an experimental preclinical model of skin with cutaneous field cancerization after chronic UV-B light exposure in an immunologically intact mouse model (SKH1 aged mice). We observed impairments in the transepidermal water loss, stratum corneum hydrat...

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Detalles Bibliográficos
Autores principales: Santiago, Juan Luis, Muñoz-Rodriguez, Jose Ramon, de la Cruz-Morcillo, Miguel Angel, Villar-Rodriguez, Clara, Gonzalez-Lopez, Lucia, Aguado, Carolina, Nuncia-Cantarero, Miriam, Redondo-Calvo, Francisco Javier, Perez-Ortiz, Jose Manuel, Galan-Moya, Eva Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8394893/
https://www.ncbi.nlm.nih.gov/pubmed/34439089
http://dx.doi.org/10.3390/cancers13163935