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Naja atra Cardiotoxin 1 Induces the FasL/Fas Death Pathway in Human Leukemia Cells

This study aimed to investigate the mechanistic pathway of Naja atra (Taiwan cobra) cardiotoxin 1 (CTX1)–induced death of leukemia cell lines U937 and HL-60. CTX1 increased cytoplasmic Ca(2+) and reactive oxygen species (ROS) production, leading to the death of U937 cells. It was found that Ca(2+)-i...

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Detalles Bibliográficos
Autores principales: Chiou, Jing-Ting, Wang, Liang-Jun, Lee, Yuan-Chin, Chang, Long-Sen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8394927/
https://www.ncbi.nlm.nih.gov/pubmed/34440842
http://dx.doi.org/10.3390/cells10082073