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Naja atra Cardiotoxin 1 Induces the FasL/Fas Death Pathway in Human Leukemia Cells
This study aimed to investigate the mechanistic pathway of Naja atra (Taiwan cobra) cardiotoxin 1 (CTX1)–induced death of leukemia cell lines U937 and HL-60. CTX1 increased cytoplasmic Ca(2+) and reactive oxygen species (ROS) production, leading to the death of U937 cells. It was found that Ca(2+)-i...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8394927/ https://www.ncbi.nlm.nih.gov/pubmed/34440842 http://dx.doi.org/10.3390/cells10082073 |