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Mechanistic Illustration: How Newly-Formed Blood Vessels Stopped by the Mineral Blocks of Bone Substitutes Can Be Avoided by Using Innovative Combined Therapeutics

One major limitation for the vascularization of bone substitutes used for filling is the presence of mineral blocks. The newly-formed blood vessels are stopped or have to circumvent the mineral blocks, resulting in inefficient delivery of oxygen and nutrients to the implant. This leads to necrosis w...

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Detalles Bibliográficos
Autores principales: Bornert, Fabien, Clauss, François, Hua, Guoqiang, Idoux-Gillet, Ysia, Keller, Laetitia, Fernandez De Grado, Gabriel, Offner, Damien, Smaida, Rana, Wagner, Quentin, Fioretti, Florence, Kuchler-Bopp, Sabine, Schulz, Georg, Wenzel, Wolfgang, Gentile, Luca, Risser, Laurent, Müller, Bert, Huck, Olivier, Benkirane-Jessel, Nadia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8394928/
https://www.ncbi.nlm.nih.gov/pubmed/34440156
http://dx.doi.org/10.3390/biomedicines9080952