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Chronic Fentanyl Self-Administration Generates a Shift toward Negative Affect in Rats during Drug Use
Drug addiction is thought to be driven by negative reinforcement, and it is thought that a shift from positive affect upon initial exposure to negative affect after chronic exposure to a drug is responsible for maintaining self-administration (SA) in addicted individuals. This can be modeled in rats...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8394963/ https://www.ncbi.nlm.nih.gov/pubmed/34439683 http://dx.doi.org/10.3390/brainsci11081064 |