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Dendritic Cells Pulsed with Cytokine-Adjuvanted Tumor Membrane Vesicles Inhibit Tumor Growth in HER2-Positive and Triple Negative Breast Cancer Models

Dendritic cells (DCs) are the most effective antigen presenting cells for the development of T cell responses. The only FDA approved DC-based immunotherapy to date is Sipuleucel-T, which utilizes a fusion protein to stimulate DCs ex vivo with GM-CSF and simultaneously deliver the antigen PAP for pro...

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Detalles Bibliográficos
Autores principales: Munoz, Luis E., Monterroza, Lenore, Bommireddy, Ramireddy, Shafizadeh, Yalda, Pack, Christopher D., Ramachandiran, Sampath, Reddy, Shaker J. C., Selvaraj, Periasamy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8395038/
https://www.ncbi.nlm.nih.gov/pubmed/34445092
http://dx.doi.org/10.3390/ijms22168377