Cargando…
Dendritic Cells Pulsed with Cytokine-Adjuvanted Tumor Membrane Vesicles Inhibit Tumor Growth in HER2-Positive and Triple Negative Breast Cancer Models
Dendritic cells (DCs) are the most effective antigen presenting cells for the development of T cell responses. The only FDA approved DC-based immunotherapy to date is Sipuleucel-T, which utilizes a fusion protein to stimulate DCs ex vivo with GM-CSF and simultaneously deliver the antigen PAP for pro...
Autores principales: | Munoz, Luis E., Monterroza, Lenore, Bommireddy, Ramireddy, Shafizadeh, Yalda, Pack, Christopher D., Ramachandiran, Sampath, Reddy, Shaker J. C., Selvaraj, Periasamy |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8395038/ https://www.ncbi.nlm.nih.gov/pubmed/34445092 http://dx.doi.org/10.3390/ijms22168377 |
Ejemplares similares
-
Metformin reduces PD-L1 on tumor cells and enhances the anti-tumor immune response generated by vaccine immunotherapy
por: Munoz, Luis Enrique, et al.
Publicado: (2021) -
Tumor Membrane Vesicle Vaccine Augments the Efficacy of Anti-PD1 Antibody in Immune Checkpoint Inhibitor-Resistant Squamous Cell Carcinoma Models of Head and Neck Cancer
por: Bommireddy, Ramireddy, et al.
Publicado: (2020) -
Hemagglutinin virus-like particles incorporated with membrane-bound cytokine adjuvants provide protection against homologous and heterologous influenza virus challenge in aged mice
por: Park, Bo Ryoung, et al.
Publicado: (2023) -
Expression of tdTomato and luciferase in a murine lung cancer alters the growth and immune microenvironment of the tumor
por: Huang, Lei, et al.
Publicado: (2021) -
Influenza Virus-like Particle-Based Hybrid Vaccine Containing RBD Induces Immunity against Influenza and SARS-CoV-2 Viruses
por: Bommireddy, Ramireddy, et al.
Publicado: (2022)