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Gran1: A Granulysin-Derived Peptide with Potent Activity against Intracellular Mycobacterium tuberculosis

Granulysin is an antimicrobial peptide (AMP) expressed by human T-lymphocytes and natural killer cells. Despite a remarkably broad antimicrobial spectrum, its implementation into clinical practice has been hampered by its large size and off-target effects. To circumvent these limitations, we synthes...

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Detalles Bibliográficos
Autores principales: Noschka, Reiner, Wondany, Fanny, Kizilsavas, Gönül, Weil, Tanja, Weidinger, Gilbert, Walther, Paul, Michaelis, Jens, Stenger, Steffen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8395039/
https://www.ncbi.nlm.nih.gov/pubmed/34445098
http://dx.doi.org/10.3390/ijms22168392