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Red Light Irradiation In Vivo Upregulates DJ-1 in the Retinal Ganglion Cell Layer and Protects against Axotomy-Related Dendritic Pruning

Retinal ganglion cells (RGCs) undergo dendritic pruning in a variety of neurodegenerative diseases, including glaucoma and autosomal dominant optic atrophy (ADOA). Axotomising RGCs by severing the optic nerve generates an acute model of RGC dendropathy, which can be utilized to assess the therapeuti...

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Detalles Bibliográficos
Autores principales: Beirne, Kathy, Freeman, Thomas J., Rozanowska, Malgorzata, Votruba, Marcela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8395066/
https://www.ncbi.nlm.nih.gov/pubmed/34445085
http://dx.doi.org/10.3390/ijms22168380