Efficient Neuroprotective Rescue of Sacsin-Related Disease Phenotypes in Zebrafish

Autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS) is a multisystem hereditary ataxia associated with mutations in SACS, which encodes sacsin, a protein of still only partially understood function. Although mouse models of ARSACS mimic largely the disease progression seen in humans,...

Descripción completa

Detalles Bibliográficos
Autores principales: Naef, Valentina, Marchese, Maria, Ogi, Asahi, Fichi, Gianluca, Galatolo, Daniele, Licitra, Rosario, Doccini, Stefano, Verri, Tiziano, Argenton, Francesco, Morani, Federica, Santorelli, Filippo M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8395086/
https://www.ncbi.nlm.nih.gov/pubmed/34445111
http://dx.doi.org/10.3390/ijms22168401

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8395086/
https://www.ncbi.nlm.nih.gov/pubmed/34445111
http://dx.doi.org/10.3390/ijms22168401

Ejemplares similares