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Efficient Neuroprotective Rescue of Sacsin-Related Disease Phenotypes in Zebrafish

Autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS) is a multisystem hereditary ataxia associated with mutations in SACS, which encodes sacsin, a protein of still only partially understood function. Although mouse models of ARSACS mimic largely the disease progression seen in humans,...

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Detalles Bibliográficos
Autores principales:	Naef, Valentina, Marchese, Maria, Ogi, Asahi, Fichi, Gianluca, Galatolo, Daniele, Licitra, Rosario, Doccini, Stefano, Verri, Tiziano, Argenton, Francesco, Morani, Federica, Santorelli, Filippo M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8395086/ https://www.ncbi.nlm.nih.gov/pubmed/34445111 http://dx.doi.org/10.3390/ijms22168401

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