Long-Chain Acyl-Carnitines Interfere with Mitochondrial ATP Production Leading to Cardiac Dysfunction in Zebrafish

In the human heart, the energy supplied by the production of ATP is predominately accomplished by ß-oxidation in mitochondria, using fatty acids (FAs) as the primary fuel. Long-chain acylcarnitines (LCACs) are intermediate forms of FA transport that are essential for FA delivery from the cytosol int...

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Detalles Bibliográficos
Autores principales: Park, Deung-Dae, Gahr, Bernd M., Krause, Julia, Rottbauer, Wolfgang, Zeller, Tanja, Just, Steffen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8395116/
https://www.ncbi.nlm.nih.gov/pubmed/34445174
http://dx.doi.org/10.3390/ijms22168468

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8395116/
https://www.ncbi.nlm.nih.gov/pubmed/34445174
http://dx.doi.org/10.3390/ijms22168468

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