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Long-Chain Acyl-Carnitines Interfere with Mitochondrial ATP Production Leading to Cardiac Dysfunction in Zebrafish
In the human heart, the energy supplied by the production of ATP is predominately accomplished by ß-oxidation in mitochondria, using fatty acids (FAs) as the primary fuel. Long-chain acylcarnitines (LCACs) are intermediate forms of FA transport that are essential for FA delivery from the cytosol int...
Autores principales: | Park, Deung-Dae, Gahr, Bernd M., Krause, Julia, Rottbauer, Wolfgang, Zeller, Tanja, Just, Steffen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8395116/ https://www.ncbi.nlm.nih.gov/pubmed/34445174 http://dx.doi.org/10.3390/ijms22168468 |
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