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Integrin αv and Vitronectin Prime Macrophage-Related Inflammation and Contribute the Development of Dry Eye Disease

Cell signaling mediated by the αv integrin plays a pivotal role in macrophage activation in various inflammatory processes, but its involvement in the pathogenesis of dry eye disease (DED) remains unclear. In a murine model of DED, we found increased αv integrin expression in ocular surface macropha...

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Detalles Bibliográficos
Autores principales: Ho, Tsung-Chuan, Yeh, Shu-I, Chen, Show-Li, Tsao, Yeou-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8395123/
https://www.ncbi.nlm.nih.gov/pubmed/34445121
http://dx.doi.org/10.3390/ijms22168410