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An Update on the Role of Nrf2 in Respiratory Disease: Molecular Mechanisms and Therapeutic Approaches

Nuclear factor erythroid 2-related factor (Nrf2) is a transcriptional activator of the cell protection gene that binds to the antioxidant response element (ARE). Therefore, Nrf2 protects cells and tissues from oxidative stress. Normally, Kelch-like ECH-associated protein 1 (Keap1) inhibits the activ...

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Detalles Bibliográficos
Autores principales: Lee, Jooyeon, Jang, Jimin, Park, Sung-Min, Yang, Se-Ran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8395144/
https://www.ncbi.nlm.nih.gov/pubmed/34445113
http://dx.doi.org/10.3390/ijms22168406